Table 4. MIS-C characteristics of published studies and this study

Variables Feldstein et al. [25],USA (n = 186) You et al. [26],Korea (n = 22) This study,Korea (n = 22)
Age (year) 8.3 8.6 9.1
Male sex 115 (61.8) 10 (45.5) 11 (50.0)
Met KD criteria 74 (39.8)1) 20 (90.9) 19 (86.4)
Complete KD 49 (26.3) 13 (59.1) 11 (50.0)
Platelet count (103 /μL) 133 251 130
CRP (mg/dL) 17.8 9.4 10.1
Initial IVIG 144 (77.4) 17 (77.3) 22 (100.0)
Initial treatment failure (i.e., IVIG resistance) 77 (41.4) 4 (23.5)2) 7 (31.8)
Biologics (IL-1 or IL-6 inhibitor) 38 (20.4) 0 (0.0) 1 (4.5)
Vasoactive agents 90 (48.4) 3 (13.6) 5 (22.7)
ICU admission 140 (75.3) NA 5 (22.7)
Coronary artery aneurysm (i.e., Z-score > 2.5) 15 (8.1) NA 3 (13.6)3)
Mortality 4 (2.1) 0 (0.0) 0 (0.0)
Data are presented as frequency (%) or median.
Almost three-quarters (73.6%, 137/186) of patients with MIS-C had KD-like features (e.g., rash, conjunctivitis, or mucositis), but less than half (39.8%, 74/186) of patients met the criteria for KD.
Of the 17 patients treated with IVIG, four (23.5%, 4/17) were resistant to IVIG treatment.
Of the 5 patients with coronary artery complications, three (13.6%, 5/22) had coronary artery aneurysms (i.e., Z-score > 2.5).
MIS-C: multisystem inflammatory syndrome in children; KD: Kawasaki disease; CRP: C-reactive protein; IVIG: intravenous immunoglobulin; IL: interleukin; ICU: intensive care unit; NA: not available.