Table 3. Performance of Japanese risk scores for predicting IVIG resistance (by age group)

Group	Risk score	Sens	Spec	PPV	NPV	Acc	AUC
Overall(n = 10,352)	Kobayashi	0.46	0.77	0.28	0.88	0.72	0.66
	Egami	0.47	0.73	0.26	0.88	0.69	0.64
	Sano	0.33	0.86	0.33	0.87	0.78	0.64
< 6 m(n = 957)	Kobayashi	0.45	0.77	0.20	0.91	0.73	0.66
	Egami	0.47	0.68	0.17	0.91	0.66	0.63
	Sano	0.27	0.88	0.23	0.90	0.81	0.61
6–11 m(n = 1,354)	Kobayashi	0.53	0.73	0.22	0.92	0.71	0.66
	Egami	0.49	0.77	0.23	0.91	0.74	0.68
	Sano	0.35	0.90	0.33	0.91	0.83	0.66
12–59 m(n = 6,799)	Kobayashi	0.44	0.79	0.30	0.87	0.73	0.66
	Egami	0.46	0.73	0.26	0.87	0.69	0.63
	Sano	0.34	0.86	0.33	0.86	0.77	0.64
≥ 60 m(n = 1,242)	Kobayashi	0.50	0.74	0.32	0.86	0.69	0.68
	Egami	0.48	0.74	0.30	0.86	0.69	0.65
	Sano	0.31	0.86	0.34	0.84	0.75	0.62

IVIG: intravenous immunoglobulin; Sens, sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value; Acc, accuracy; AUC, area under the receiver operating characteristic curve.