| Clinical/anatomic situation | Suggested first-line |
|---|---|
| Symptomatic/objective ischemia in focal, accessible lesion(s) | PCI |
| Left-main (esp. proximal) or bilateral ostial high-risk stenosis | CABG preferred (PCI bridge if single, discrete lesion) |
| Stenosis at giant CAA neck / suboptimal stent landing zones | CABG ± selective PCI adjunct (heart-team) |
| Progressive stenosis or recurrent thrombosis despite optimal therapy | Individualized (PCI or CABG) |
| Acute PCI complications (perforation) | Emergency PCI; covered stent bail-out |